TCSB-107-EM03-02-E013

107

960 千元

毒物及化學物質評估與管理-毒性化學物質評估及管理

2018/09/18

2019/03/17

陳永仁

化學局

崔君至

臺北市立大學

化學物質管理

關注化學物質；毒理資料庫；審核機制

Concerned Chemical Substances; Toxicology Database; Audit Mechanism

林于凱

林于凱

02-28718288#8332

yklin@utaipei.edu.tw

「毒性及關注化學物質管理法」於108年1月16日經總統公布，使我國毒物及化學物質源頭管理工作再向前邁進。因應毒管法修正及未來關注化學物質之擴大列管，未來必須掌握列管物質完善之毒理資料，優先規劃資料庫格式欄位及營運管理作法，以作為主管機關行政管制之支撐依據。本計畫在毒理資料庫前期規劃之產出結果主要有三：在「研析我國化學物質毒理資料庫發展之邊界與範疇」部分，蒐集國內外10種以上常用資料庫之毒理資訊進行研析，制定如物質摘要、製造與使用、物理與化學性質、安全使用及應變管理、急毒性、致癌性、遺傳、生殖及發育毒性、系統毒性、環境蓄積性與生態毒性及暴露標準與規定等制式欄位，並選定10種眾所皆知之化學物質完成案例撰寫；在「規劃毒理資料庫資訊來源及未來營運管理方式」部分，提出優先納入化學物質之項目，除已列管之毒性化學物質，尚包含有食安疑慮物質、毒品先驅物質及爆裂先驅物質，作為第一批預計列管及選定納入資料庫之物質群組，並提出與現行化學物質相關資料庫進行聯結之作法；在其他行政支援部分，本計畫亦已評析資料庫數據引用、資料來源審核及定期操作化學局租賃之資料庫再提出回饋，並完成3場次化學物質資料庫相關議題之專家學者諮詢會議。

關注化學物質；毒理資料庫；審核機制

期末報告.pdf

13MB

期末報告全文

2019/5/22 上午 12:00:00

To promote the managing efficiencies of the toxic and chemical substances from very beginning in Taiwan, the Toxic and Concerned Chemical Substances Control Act was promulgated on January 16, 2019. For supporting the administrative control of the competent authorities and in view of the amendments to the Toxic Chemical Substances Control Act and the upcoming expansion of concerned chemical substances, it is necessary to grasp the complete toxicological information of the control substances and prioritize the layout of the database and the operational management practices. The main results of this project can be divided into three sections. In the section ”Analysis of the boundaries and categories of the development of toxicology databases in Taiwan”, analyze the toxicological information of more than 10 items of commonly used international databases. Developing standard formats such as Substance Identification, Manufacturing and Use, Physical and Chemical properties, Safety and Handling, Acute Toxicity, Carcinogenicity, Genetic, Reproductive and Developling Toxicity, Environmental accumulation and Ecotoxicity, Exposure Standards and Regulations and selected 10 well-known chemical substances to complete the case writing. In the section ”Planning toxicological database information resources and future operational management methods”, propose that prioritize the inclusion of chemical substances, in addition to the toxic chemicals already in the possession, contain food safety substances, drug precursors and Improvised Explosive Device as the first group of substances expected to be listed and selected for inclusion in the database and also proposes a method of linking with the current chemical substance-related database. Finally, as for administrative support, we have also reviewed database, data references, data source audits and regular operation of the Toxic and Chemical Substances Bureau's leased database to provide feedback, and have completed three expert and scholar consultation meetings to discuss chemical substance database related issues.

Concerned Chemical Substances; Toxicology Database; Audit Mechanism