環保專案成果報告查詢系統

專案計畫編號
經費年度	111
計畫經費	1,800 千元
預算科目	水污染防治及水體水質改善
專案開始日期	2022/02/16
專案結束日期	2022/12/31
專案主持人	李彥芬
主辦單位	環檢所
承辦人	王姿惠
執行單位	財團法人工業技術研究院
專案分類	水質保護、化學物質管理
中文關鍵字	有機錫、放流水、毒化物
英文關鍵字	Organotin, Effluent, Toxic and Chemical Substances
協同主持人
共同主持人
計畫聯絡人	李彥芬
計畫聯絡電話	03-5732327#
計畫聯絡信箱	yflee@itri.org.tw

中文摘要	本計畫蒐集有機錫相關文獻與分析技術評析，完成二月桂酸二丁錫及二氯化二丁錫LC/MS/MS分析參數確認、層析條件測試及檢量線建立，以此條件執行放流水中有機錫化合物檢測方法開發所需之品保品管要求，其中二月桂酸二丁錫及二氯化二丁錫方法偵測極限分別為0.853及0.212 μg/L，符合應揭露之有機錫類排放廢(污)水污染物濃度推估值之要求。在公告列管毒化物部分完成三種儀器測試，包括Pyr-GC/MS、GC/MS及LC/MS/MS，本團隊建議毒化物分析可先由熱裂解之EGA模式作初步定性，再由LC/MS/MS定量，避免樣品衍生化程序，同時分析三丁基錫、氯化三苯錫及氯化三丙錫等有機錫化合物。由於有機錫化合物為配位金屬化合物，其金屬原有鍵結之配位基容易被取代，當樣品同時含有相同數目之烷基或芳香基時，分析上不易達到定性目的，經本團隊測試，以液相層析串聯式質譜儀可同時分析三丁基錫、氯化三苯錫及氯化三丙錫，建議在列管毒性化學物質管理上參考國外之策略，以總量管制方式評估毒性較強之三丁基錫及三苯基錫，避免分析上之基質效應導致誤判等問題。
中文關鍵字	有機錫、放流水、毒化物

中文摘要

本計畫蒐集有機錫相關文獻與分析技術評析，完成二月桂酸二丁錫及二氯化二丁錫LC/MS/MS分析參數確認、層析條件測試及檢量線建立，以此條件執行放流水中有機錫化合物檢測方法開發所需之品保品管要求，其中二月桂酸二丁錫及二氯化二丁錫方法偵測極限分別為0.853及0.212 μg/L，符合應揭露之有機錫類排放廢(污)水污染物濃度推估值之要求。在公告列管毒化物部分完成三種儀器測試，包括Pyr-GC/MS、GC/MS及LC/MS/MS，本團隊建議毒化物分析可先由熱裂解之EGA模式作初步定性，再由LC/MS/MS定量，避免樣品衍生化程序，同時分析三丁基錫、氯化三苯錫及氯化三丙錫等有機錫化合物。由於有機錫化合物為配位金屬化合物，其金屬原有鍵結之配位基容易被取代，當樣品同時含有相同數目之烷基或芳香基時，分析上不易達到定性目的，經本團隊測試，以液相層析串聯式質譜儀可同時分析三丁基錫、氯化三苯錫及氯化三丙錫，建議在列管毒性化學物質管理上參考國外之策略，以總量管制方式評估毒性較強之三丁基錫及三苯基錫，避免分析上之基質效應導致誤判等問題。

中文關鍵字

有機錫、放流水、毒化物

類型	檔名	檔案大小	說明	最新版公開日期
期末報告	放流水中有機錫分析技術開發計畫期末報告定稿_1111213.pdf	11MB	放流水中有機錫分析技術開發計畫報告定稿	2023/2/17 上午 12:00:00

摘要	In this project, literatures related to the analysis technologies of organotin were reviewed. Also, analytical parameters of dibutyltin dilaurate and dibutyltin dichloride in LC/MS/MS were confirmed and chromatographic conditions and calibration curve were established. Quality control requirements of dibutyltin dilaurate and dibutyltin dichloride analysis method in the outfall water were also established. The method detection limits of the dibutyltin dilaurate and dibutyltin dichloride are 0.853 and 0.212 μg/L, respectively, which meet the requirements of the law enforcement. Requirements for the estimated concentration of the disclosed organotin discharge waste water pollutants. Three kinds of instrument tests have been completed in the announcement of toxic substances, including Pyr-GC/MS, GC/MS, and LC/MS/MS. Recommends were made that the toxic substances analysis can be preliminarily characterized by EGA mode of Py-GC/MS, and then by LC /MS/MS quantification, avoids sample derivatization procedures, and can simultaneously analyze organotin compounds such as butyltin, triphenyltin chloride and tripropyltin chloride. Since the organotin compound is a coordination compound, the original bonding group to the metal will be easily substituted. When the sample contains more than two kinds of organotin compounds with the same butyl group, it is easy to cause a qualitative misjudgment. After some modification, tributyltin, triphenyltin chloride and tripropyltin chloride can be simultaneously analyzed with liquid chromatography tandem mass spectrometer. It is recommended to follow strategies in other countries for the management of organotin, and evaluate the toxicity by sum of organotin homologues with same number of branch to avoid problems such as misjudgment caused by matrix effect in analysis.
英文關鍵字	Organotin, Effluent, Toxic and Chemical Substances

摘要

In this project, literatures related to the analysis technologies of organotin were reviewed. Also, analytical parameters of dibutyltin dilaurate and dibutyltin dichloride in LC/MS/MS were confirmed and chromatographic conditions and calibration curve were established. Quality control requirements of dibutyltin dilaurate and dibutyltin dichloride analysis method in the outfall water were also established. The method detection limits of the dibutyltin dilaurate and dibutyltin dichloride are 0.853 and 0.212 μg/L, respectively, which meet the requirements of the law enforcement. Requirements for the estimated concentration of the disclosed organotin discharge waste water pollutants. Three kinds of instrument tests have been completed in the announcement of toxic substances, including Pyr-GC/MS, GC/MS, and LC/MS/MS. Recommends were made that the toxic substances analysis can be preliminarily characterized by EGA mode of Py-GC/MS, and then by LC /MS/MS quantification, avoids sample derivatization procedures, and can simultaneously analyze organotin compounds such as butyltin, triphenyltin chloride and tripropyltin chloride. Since the organotin compound is a coordination compound, the original bonding group to the metal will be easily substituted. When the sample contains more than two kinds of organotin compounds with the same butyl group, it is easy to cause a qualitative misjudgment. After some modification, tributyltin, triphenyltin chloride and tripropyltin chloride can be simultaneously analyzed with liquid chromatography tandem mass spectrometer. It is recommended to follow strategies in other countries for the management of organotin, and evaluate the toxicity by sum of organotin homologues with same number of branch to avoid problems such as misjudgment caused by matrix effect in analysis.

英文關鍵字

Organotin, Effluent, Toxic and Chemical Substances