EPA-92-FA12-03-A010

092

10,510 千元

2003/03/12

2003/12/31

李俊璋

空保處

國立成功大學環境微量毒物研究中心

化學物質管理

戴奧辛,血清,居民,垃圾焚化廠,食物

Incinerators,PCDDs/PCDFs,Residents,Serum,Dietary Intake

郭育良、蘇慧貞、桂椿雄、廖寶琦

李俊璋

06-2353535-5596

cclee@mail.ncku.edu.tw

本計畫分別於新竹市、台中縣后里及高雄縣仁武等三座焚化廠附近地區進行居民之健康檢查、健康問卷、飲食問卷及時間活動模式調查與血液採樣工作，新竹市、台中縣后里及高雄縣仁武等三座焚化廠附近居民實際參與本研究者分別為94、108及84人，全部共完成255個符合品管規範之血清樣本。新竹市、台中縣后里及高雄縣仁武等三座焚化廠附近居民血液中多氯戴奧辛/?喃毒性當量平均濃度分別為22.6、25.9及21.6 pg WHO98-TEQDF/g lipid，三廠居民之多氯戴奧辛/?喃毒性當量平均濃度為20.6 pg I-TEQ/g lipid與日本及韓國等亞洲國家一般居民之平均濃度範圍相近（13.47-23.8 pg I-TEQ/g lipid）。 綜合四年共執行十九焚化廠鄰近居民血液中戴奧辛濃度調查之結果，發現以暴露評估角度而言，台灣地區各區域民眾血液中多氯戴奧辛及多氯?喃濃度確實有顯著之差異，此造成血液濃度分布有所差異原因可能來自於空氣暴露或飲食暴露來源等。但是由本研究四年以來的研究結果顯示，以台灣地區焚化爐較短之操作時間而言，目前並無證據顯示鄰近焚化爐的居民受到焚化爐所排放的多氯戴奧辛及?喃暴露，而導致累積於體內使得血液中戴奧辛濃度值增高之情形，此論點經由釐清飲食影響後仍發現一樣的結果。 依據風險評估結果顯示，只計算17種多氯戴奧辛及?喃之終生平均暴露劑量時，約有9％民眾之終生平均暴露劑量高於世界衛生組織訂定之高限值4 pg WHO-TEQ/kg/day，另約有60％民眾之終生平均暴露劑量高於歐盟將於2004年執行之14 pg WHO-TEQ/kg/week（2 pg WHO-TEQ/kg/day）。顯示台灣地區部分居民之戴奧辛暴露劑量仍偏高，應積極擬訂並執行戴奧辛污染源管制及減量措施。

戴奧辛,血清,居民,垃圾焚化廠,食物

0000007260.zip

5MB

[期末報告]公開完整版

2004/2/1 上午 12:00:00

The study was conducted to build up the background information of serum dioxins concentration, health status, dietary pattern of residents living near the incinerators in Hsin-Chu City, Hou-Li of Taichung Country, and Jen-Yu of Kaohsiung County. The average serum PCDD/Fs level was 22.6, 25.9 and 21.6 pg WHO98-TEQDF/g lipid, respectively. In addition, the r associate the consumption frequency of different food groups (milk, eggs, fish, and others) and the levels of serum polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) concentrations of residents living near a municipal waste incinerator. All selected subjects were between 18-65 years old and proportionally chosen from each age group based on population distribution. In addition, they had to have lived within a 5-km radius of the incinerator for at least 5 years. Trained interviewers administered a dietary questionnaire interview. Higher serum PCDD/F levels were found in older than in younger subjects, and higher PCDD/F concentrations were found in females than in males. An analysis between the consumption frequency of different foods and serum PCDD/F levels showed that fish might have contributed the highest quantity of measured serum PCDD/Fs. Yet, the regression coefficient of dietary intake and PCDD/F concentration was only 0.017 before and 0.105 after adjusting for the variables of age, gender, and smoking status of the study subjects. Frequency of fish consumption may be the most significant contributor to serum PCDD/F levels. Further research is needed to quantify the association between the consumption of various food groups and their potential contributions to corresponding serum PCDD/F concentrations.

Incinerators,PCDDs/PCDFs,Residents,Serum,Dietary Intake